Treatment for uncomplicated gonorrhea with suspected chlamydial coinfection?

• A. Ceftriaxone IM plus doxycycline
• B. Doxycycline alone
• C. Azithromycin alone
• D. Cefixime alone

Answer: (A)

Treating gonorrhea when chlamydial coinfection is suspected calls for covering both organisms at once. Ceftriaxone given by intramuscular injection reliably treats Neisseria gonorrhoeae, and adding doxycycline provides therapy for Chlamydia trachomatis. This dual approach addresses the common coinfection and counters evolving resistance better than any single-agent regimen. Doxycycline or azithromycin alone won’t clear gonorrhea, and cefixime alone is less reliable due to resistance. So the combination of ceftriaxone and doxycycline is the best choice.